"Bacteria never die, they just phage away..." Mark Mueller

T4 lysis and lysis inhibition

Characterization of the proteins involved in lysis and lysis inhibition in bacteriophage T4 using genetic, biochemical, and biophysical techniques.

Characterization of the QB infection cycle

Determine the mechanism of MurA inhibition by A2 and how lysis timing is controlled within this system.

How do holins control lysis timing and its mechanism?

Biochemical and genetic characterization of bacteriophage holin.

How do Spanins work in phage lysis?

The final step in phage infection is lysis of the host cell.

So let us summon a new spirit of patriotism; of service and responsibility where each of us resolves to pitch in and work harder and look after not only ourselves, but each other...."